Blar i forfatter "Méplan, Catherine"

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    • Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status 

      Fedirko, Veronika; Jenab, Mazda; Méplan, Catherine; Jones, Jeb S.; Zhu, Wanzhe; Schomburg, Lutz; Siddiq, Afshan; Hybsier, Sandra; Overvad, Kim; Tjønneland, Anne; Omichessan, Hanane; Perduca, Vittorio; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katzke, Verena; Aleksandrova, Krasimira; Trichopoulou, Antonia; Karakatsani, Anna; Kotanidou, Anastasia; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Agnoli, Claudia; Naccarati, Alessio; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Weiderpass, Elisabete; Skeie, Guri; Nøst, Therese Haugdahl; Lujan-Barroso, Leila; Quirós, Jose Ramón; Huerta, José María; Rodríguez-Barranco, Miguel; Barricarte, Aurelio; Gylling, Björn; Harlid, Sophia; Bradbury, Kathryn Erica; Wareham, Nick; Khaw, Kay-Tee; Gunter, Marc J.; Murphy, Neil; Freisling, Heinz; Tsilidis, Kostas; Aune, Dagfinn; Riboli, Elio; Hesketh, John E.; Hughes, David J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-25)
      Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the risk of colorectal cancer (CRC) development. We examined the association between CRC risk and genotype for single nucleotide polymorphisms (SNPs) in selenoprotein and Se metabolic pathway genes. <i>Illumina Goldengate</i> assays were designed and resulted in the genotyping of 1040 variants in 154 genes ...

    • Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study 

      Hughes, David J.; Schomburg, Lutz; Jenab, Mazda; Biessy, Carine; Méplan, Catherine; Moskal, Aurelie; Sun, Qian; Demircan, Kamil; Fedirko, Veronika; Weiderpass Vainio, Elisabete; Mukhtar, Maryam; Olsen, Anja; Tjønneland, Anne; Overvad, Kim; Schulze, Matthias; Nøst, Therese Haugdahl; Skeie, Guri; Olsen, Karina Standahl; Ricceri, Fulvio; Grioni, Sara; Palli, Domenico; Masala, Giovanna; Tumino, Rosario; Pasanisi, Fabrizio; Amiano, Pilar; Colorado Yohar, Sandra M.; Agudo, Antonio; Sánchez, Maria-Jose; Ardanaz, Eva; Sund, Malin; Andersson, Anne; Perez-Cornago, Aurora; Travis, Ruth; Heath, Alicia K.; Dossus, Laure (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-01)
      Selenium (Se) may help prevent breast cancer (BC) development. Owing to limited observational evidence, we investigated whether prediagnostic Se status and/or variants in the selenoprotein genes are associated with BC risk in a large European cohort. Se status was assessed by plasma measures of Se and its major circulating proteins, selenoprotein P (SELENOP) and glutathione peroxidase 3 (GPX3), in ...